Rhodiola has been used in traditional medicinal herbs in the Chinese region of Siberia and Ukraine. In the former Soviet Union, it should be used as a kind of adaptation to reduce fatigue and enhance the body's natural resistance to various pressures. In Siberia, it is said that "insisting on drinking Rhodiola tea can live beyond 100 years". Rhodiola has traditionally been used for sexual dysfunction in men and women. In the former Soviet Union, a very popular formulation of the herb is a tincture called "nastojka", which is made by mixing fresh Rhodiola with 40% alcohol and placing it for a week. A teaspoon of "nastojka" after every meal is used as a prescription for patients with sexual dysfunction. In Siberia, especially in cold, wet winter, people often take Rhodiola rosea to prevent disease. In Mongolia, it is used for the treatment of tuberculosis and cancer.

Nearly 200 different Rhodiola species have been identified. Only 14 species have been studied and found that the chemical constituents and pharmacological activities of Rhodiola sachalinensis are closely related to their species. Its unique chemical active components are rosavin (the most active), rosin, rosarin, rhodiolin and salidroside. Rhodiola rosea contains rosavin, rosin and rosarin.

The root and rhizome of Rhodiola were crushed into coarse powder and extracted with 70% ethanol to extract the extract. The extract was extracted and decompressed to recover ethanol. The concentration solution was stirred evenly with equal amount of water, and the filtrate was treated 3 times, and the filtrate was decompressed and concentrated. The extract was extracted with petroleum ether, chloroform, ethyl acetate and n-butanol, ethyl acetate and n-butanol in turn. Some solvents were recovered, crude Tyrol and salidroside were obtained.