As global aging accelerates and consumer awareness of healthy living continues to rise, the anti-aging and precision nutrition industry is experiencing rapid growth. Rather than focusing solely on lifespan, modern health science increasingly emphasizes Healthspan — the number of years people live in good health.

In the dietary supplement and nutraceutical industries, several longevity ingredients are gaining significant attention due to their scientific validation and formulation potential.
In Q1 2026, five ingredients have emerged as key drivers of the longevity nutrition market:
NAD+ Precursors
Alpha-Ketoglutarate (AKG)
Pyrroloquinoline Quinone (PQQ)
Resveratrol
Ergothioneine
These ingredients support multiple biological pathways related to aging, including mitochondrial function, cellular energy metabolism, oxidative stress protection, and autophagy regulation.
For dietary supplement brands and formulation developers, understanding these ingredients is essential for developing next-generation longevity products.
NAD+ (Nicotinamide Adenine Dinucleotide) plays a central role in cellular metabolism and energy production. As NAD+ levels naturally decline with age, supplementation strategies using NAD+ precursors have become a major focus in longevity science.
Common NAD+ precursors include:
· NMN (Nicotinamide Mononucleotide)
· NR (Nicotinamide Riboside)

· NADH

Recent human studies published in leading metabolic journals have demonstrated that NR and NMN supplementation can effectively elevate NAD+ levels in the bloodstream, supporting cellular energy metabolism and mitochondrial activity.
Advanced delivery technologies such as liposomal encapsulation and nano-delivery systems are also improving bioavailability, making NAD+ supplementation more efficient for modern formulations.
For supplement brands, NAD+ ingredients are increasingly used in:
* energy support formulas
* anti-aging supplements
* cognitive health products
* mitochondrial support blends
Alpha-Ketoglutarate (AKG) is a naturally occurring compound in the tricarboxylic acid (TCA) cycle, playing a critical role in cellular energy metabolism.
Resveratrol remains one of the most widely studied polyphenols associated with healthy aging

Ergothioneine is a naturally occurring antioxidant amino acid that has attracted increasing scientific attention in recent years.
Compliance has become a key competitive advantage for ingredient suppliers.
For supplement manufacturers and formulation developers, selecting reliable raw material suppliers is essential.
High-quality ingredients offer several advantages:Working with experienced ingredient manufacturers can help brands accelerate product development while ensuring supply stability.
As the global anti-aging and precision nutrition industry evolves, Shanghai Aidu Biotechnology Co., Ltd(Aidubio) has emerged as a powerhouse of innovation. With nearly a decade of expertise in anti-aging raw materials, Aidubio leverages a state-of-the-art R&D and manufacturing system to provide high-purity ingredients and customized solutions for the pharmaceutical, nutraceutical, and cosmetic sectors worldwide.
At Aidubio, we believe that "Superior Products Stem from Superior Raw Materials." Our commitment to research is backed by a global sourcing network and a modern R&D center equipped with industry-leading analytical tools, including LC-MS, GC-MS, and ICP.
Our dedication to quality is validated by international certifications, including ISO 9001, ISO 22000, and Kosher. As a core manufacturer of anti-aging extracts in China, Aidubio’s continuous technical breakthroughs have established an irreplaceable competitive advantage in the global market.
Our R&D efforts have yielded significant milestones in the longevity science field:
RejuEGT® (L-Ergothioneine): Using a proprietary patented fermentation technology, we have overcome traditional production bottlenecks. RejuEGT® offers high-purity, industrial-scale availability of this powerful antioxidant amino acid that the human body cannot synthesize on its own.
ProFisetin® (Fisetin): Developed by our specialized team, ProFisetin® has been scientifically validated through zebrafish antioxidant experiments to significantly reduce Reactive Oxygen Species (ROS) levels, demonstrating potent anti-aging efficacy.
RejuEGT® (L-Ergothioneine) ProFisetin® (Fisetin)
In addition to our flagship products, Aidubio offers a comprehensive portfolio of core anti-aging ingredients, including:
NAD+ Precursors (NMN/NR)
PQQ (Pyrroloquinoline Quinone)
Resveratrol
AKG (Alpha-Ketoglutarate)
NMN
NADH
Pterostilbene
AKG-Ca
Spermidine Trihydrochloride
To ensure seamless delivery and market compliance, Aidubio has established an integrated "Shanghai – Sichuan – USA" supply chain. With a dedicated warehouse in Los Angeles, we guarantee rapid dispatch and stable large-scale supply for the North American market.
Beyond raw materials, we provide:
Customized Delivery Technologies: Enhancing bioavailability and stability.
Formulation Support: Tailored solutions for specific product applications.
Regulatory Documentation: Full compliance support to meet global market entry requirements.
With RejuEGT® and ProFisetin® at the core, Aidubio continues to empower the anti-aging industry through scientific excellence and rigorous quality control. We invite global partners to explore the blue ocean of the longevity market together.
Contact Us:
Official Website: www.aidubio.com
Email: idusc@aidubio.com