Pterostilbene

Pterostilbene is a naturally occurring polyhydroxy stilbenoid found in sandalwood and various plants. As a methoxy analog of resveratrol, it is often referred to as the "next-generation resveratrol." Compared to resveratrol, pterostilbene exhibits higher lipophilicity, superior bioavailability, and greater stability. Research has demonstrated its enhanced potential in antioxidant, anti-proliferative, lipid-regulating, and antifungal applications, particularly attracting attention in the fields of functional foods and dietary supplements. AIDU Biotech offers a product consisting of 99% high-purity trans-pterostilbene—the biologically active form responsible for its antioxidant effects, activation of longevity proteins, and maintenance of mitochondrial function.

Product Description

Appearance: White to off-white crystalline powder

Solubility: Freely soluble in ethanol and dimethyl sulfoxide (DMSO), practically insoluble in water
CAS Number: 537-42-8
Molecular Weight: 256.3
Molecular Formula: C₁₆H₁₆O₃

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Product Specifications

Product Process and Advantages

· Bioavailability Characteristics: As a methoxylated analog of resveratrol, Pterostilbenee exhibits higher lipid solubility. This structural feature facilitates its passage across biological membranes and enhances in vivo stability. Compared to resveratrol, Pterostilbenee is metabolized more slowly, making it ideal for formulations requiring sustained nutritional support.

· High-Purity Refining Process: AIDU Biotech employs controlled multi-step purification and recrystallization processes, with strict management of critical quality parameters, ensuring Pterostilbenee raw material purity consistently reaches ≥99%. Systematic control of impurity profiles and residual solvents meets the quality and safety requirements for dietary supplement ingredients.
· Quality System & Compliant Manufacturing: All products from AIDU Biotech are manufactured in its own production facilities, with strict adherence to cGMP quality management standards, ensuring safety and reliability. The raw materials meet Non-GMO, Solvent-free, and Gluten-free criteria. Each batch undergoes comprehensive physicochemical testing prior to release, providing strong assurance for regulatory compliance in major global health markets such as the United States and the European Union.
· Supply & Delivery Capability: Leveraging R&D and manufacturing capabilities in Shanghai, combined with local warehousing resources in the U.S., AIDU Bio provides global customers with stable bulk supply, inventory support, and efficient delivery services—ideal for long-term project collaboration.

Product Functions and Mechanisms

· Antioxidant Applications: Studies indicate that Pterostilbenee participates in antioxidant-related physiological pathways and is commonly used in functional formulations designed to support the body's natural antioxidant defense systems.

· Cellular Metabolism & Healthy Aging: Scientific research has explored Pterostilbenee’s role in Sirtuin-related signaling pathways, which are closely linked to cellular energy metabolism and mitochondrial function. As a result, it is widely applied in healthy aging and cellular nutrition support products.
· Metabolic Health Support: In nutritional and functional product development, Pterostilbenee is frequently included in formulations targeting lipid levels and overall metabolic balance, making it suitable for cardiovascular and metabolic health-oriented products.

Scientific Research & Data Backing

Pterostilbenee from AIDU Biotech is not only a potent antioxidant but also a precise modulator of cellular energy and longevity pathways.

1 Activates the Cellular "Longevity Switch" (SIRT1 Activation)
Literature shows that Pterostilbenee is a powerful activator of the SIRT1 protein, aiding in DNA repair and regulation of longevity signals.

2 Upgrades the Cellular "Power Plant" (Mitochondrial Optimization)
Studies demonstrate that Pterostilbenee significantly upregulates PGC-1α expression, promotes mitochondrial biogenesis, and enhances cellular ATP production.
Key Data Comparison:
Oral Absorption Rate: Pterostilbenee (80%) vs Resveratrol (20%)
In Vivo Half-Life: Pterostilbenee (105 min) vs Resveratrol (14 min)

Literature References:

·McCormack, D., & McFadden, D. (2013). Pterostilbenee: A review of preclinical studies and clinical trials. Journal of Berry Research. (DOI: 10.3233/JBR-130054)

·Kapetanovic, I. M., et al. (2011). Pharmacokinetics, bioavailability, and metabolic profile of resveratrol and Pterostilbenee.

Applications

· Dietary Supplements: Used as a polyphenolic functional ingredient in antioxidant, healthy aging, and cardiovascular health-focused supplement formulations.

· Functional Foods & Beverages: Suitable for the development of functional foods and beverages designed to support metabolic vitality and overall nutritional replenishment.
· Cellular Nutrition & Healthy Aging Formulations: Applied in formulas targeting cellular-level nutritional support and redox balance management, meeting the raw material demands of precision health products.
· Scientific Research & Product Development: Serves as a polyphenol-derived material for fundamental research, metabolic pathway exploration, and functional validation in product development stages.

Formulation & Application Recommendations

Given Pterostilbenee’s strong lipophilicity and limited water solubility, the following approaches are recommended for formulation and application development:

·Softgel Systems: Dissolve Pterostilbenee in lipid-based carriers (e.g., lecithin or medium-chain triglyceride [MCT] oil) to enhance its dispersion and bioavailability in the gastrointestinal environment.

·Emulsification & Dispersion Technologies: Use microemulsion or nanoemulsion techniques to improve dispersion stability of Pterostilbenee in aqueous systems (e.g., functional beverages).

·Synergistic Formula Design: Combine with other fat-soluble antioxidants or oil-based matrices to increase overall solubility and stability within the formulation system.

Packaging & Storage

Packaging: 1 kg/aluminum foil bag, 25 kg/fiber drum, or customizable upon request

Storage Conditions: Keep tightly sealed, store in a cool, dry place, protected from light
Shelf Life: 24 months