Pharmacological Effects Of Epimedium Extract
- May 21, 2018 -

Influence on sexual function

Epimedium has the effect of prosper, which is due to the hypersplenism of semen, after the seminal vesicle fills with the seminal vesicle, stimulates the sensory nerve and is indirectly excited by the sexual desire. The fluid extract made from Epimedium or Japanese Epimedium can not show the tail reaction to the dog, but it has the effect of promoting the secretion of semen, and its leaves and roots have the strongest effect. The fruit is the weakest; the method of increasing weight of the prostate, seminal vesicle and anus muscle (mice) proves that the extract of Epimedium has a male hormone like effect, and its potency is weaker than that of osthole, but stronger than EEH and hippocampus. The extract is 20~40 mg of extract, and its potency is equivalent to 7.5 microgram testosterone. The decoction of Epimedium was used to remove the mice in both sides of the ovary. It proved that there was no effect of estrogen on the mating rate, the cycle of ovulation and the excretion of estrogen in the urine of the rabbit, and the results of hot water and cold water extract were the same. The ethanol extract of epimedium in Japan has no effect on the sexual cycle of normal and ovariectomized female mice, and does not increase the weight of the uterus and ovaries.

Effects on microbes

Epimedium decoction has a significant inhibitory effect on poliomyelitis virus in a test tube. In the 1 hour contact with the virus, it shows inactivation and can also be suppressed to other enteroviruses. It has a significant inhibitory effect on Staphylococcus alba and Staphylococcus aureus, and to neyzalus neicella, Diplococcus pneumoniae, and influenza bloodthirsty rods The bacteria have a mild inhibition. The 1% concentration has bacteriostasis effect on Mycobacterium tuberculosis.

Antitussive, expectorant and antiasthmatic effect

Among the various preparations of epimedium, C and epimedium II compound II (epimedium herb: Eucalyptus =8:2:1) have some expectorant effect (phenol red in mice). Ethyl acetate extracts have a preliminary antitussive effect (SO2 causes cough in mice), and the antiasthmatic effect on bronchial asthma in guinea pigs is not Ideal enough.

Other effects

The extract of Epimedium has antihypertensive effect on rabbits, small amount makes the urine secretion increase, a large amount of urine secretion is inhibited, the isolated rabbit intestines are inhibited, the isolated uterus is first excited after inhibition, oral can reduce the blood sugar of hyperglycemia rats, and the Epimedium contains vitamin E (chicken identification method).

The decoction of Xianling spleen (Epimedium Epimedium) and alcohol extract can reduce blood pressure in anesthetized rabbits, normal and renal hypertensive rats. The principle of hypotension on Xianling spleen is mainly due to the dilatation of peripheral blood vessels, and it is believed to be mainly due to the inhibition of the vascular center. Erxian mixture (Xianling spleen, cortex phellodendron, angelica, Rhizoma Anemarrhena, Rhizoma Anemarrhena, Morinda officinalis, Morinda officinalis) showed hypotensive effect on the acute experiment of anesthetized cats and dogs and hypertension dogs. It had significant antihypertensive effect on the rats with nerve type, kidney type and testis excision type hypertension, and the hypotension of the adrenal ironing type and ovariectomized type of rats was not significant. After preliminary analysis, Cortex Phellodendri and Xianling spleen were the main components in Erxian mixture.